Vaping as a risk factor for stroke
Electronic cigarettes, known as e-cigarettes or vapes, are battery-operated devices that deliver nicotine to users by turning a nicotine containing solution into a vapour that is inhaled. Vapes often come in a variety of sweet and fruity flavours.
Vapes are widely used to help smokers give up tobacco, which is worse for your health than vaping. However, vaping has been linked to negative health impacts1. Despite this, they are increasingly popular among people who did not previously smoke, especially young people.
According to a recent study in England, over a three-year period, the rate of vaping by those who were not regular smokers grew substantially – from one in 200 to one in 28. This increase was largely driven by young adults2. Additionally, around 1 in 6 adolescents have used vapes in their life, and 1 in 10 use them more regularly, across Europe3.
Vaping and cardiovascular disease
Vapes usually contain nicotine. Long-term nicotine exposure, even without the other harmful components of traditional cigarettes, can contribute to cardiovascular problems such as high blood pressure and an increased risk of heart disease and stroke. Some studies suggest that vaping may trigger inflammation in the body, including within the cardiovascular system, which is associated with cardiovascular diseases including stroke.4,5
Vaping and stroke risk: Key points
Research on the cardiovascular effects of vaping is still relatively limited compared to traditional smoking. Although vaping can help people stop smoking tobacco6, there are still negative impacts on cardiovascular health4,5. The American Heart Association (AHA) recommends that everyone should avoid tobacco products, including vapes, to reduce risk of stroke7.
There is evidence indicating that younger adults who vape may be at increased risk for cardiovascular events, including stroke, especially if they have additional risk factors like obesity, hypertension, or a family history of cardiovascular disease8.
References
- Meng XC, Guo XX, Peng ZY, Wang C, Liu R. Acute effects of electronic cigarettes on vascular endothelial function: a systematic review and meta-analysis of randomized controlled trials. Eur J Prev Cardiol. 2023;30(5):425–435. https://doi.org/10.1093/eurjpc/zwac248
- Jackson SE, Shahab L, Tattan-Birch H, Brown J. Vaping among adults in England who have never regularly smoked: a population-based study, 2016-24. Lancet Public Health. 2024;9(10):e755–e765. https://doi.org/10.1016/S2468-2667(24)00183-X
- Charrier L, Van Dorsselaer S, Canale N, Baska T, Kilibarda B, Comoretto RI, et al. A focus on adolescent substance use in Europe, central Asia and Canada. Health Behaviour in School-aged Children international report from the 2021/2022 survey. Volume 3. World Health Organization. Regional Office for Europe; 2024.https://www.who.int/europe/publications/i/item/9789289060936
- Berlowitz JB, Xie W, Harlow AF, Hamburg NM, Blaha MJ, Bhatnagar A, et al. E-cigarette use and risk of cardiovascular disease: A longitudinal analysis of the PATH study (2013-2019). Circulation. 2022;145:1557–1559. https://doi.org/10.1161/circulationaha.1 21.057369
- Zhao K, Li J, Zhou P, Xu L, Yang M. Is electronic cigarette use a risk factor for stroke? A systematic review and meta-analysis. Tob Induc Dis. 2022;:20:101. https://doi.org/10.18332/tid/154364
- Klein AP, Yarbrough K, Cole JW. Stroke, Smoking and Vaping: The No-Good, the Bad and the Ugly. Ann Public Health Res. 2021;8(1):1104. https://pubmed.ncbi.nlm.nih.gov/34322688
- Bushnell C, Kernan WN, Sharrief AZ, Chaturvedi S, Cole JW, Cornwell III WK, et al. 2024 guideline for the primary prevention of stroke: a guideline from the American Heart Association/American Stroke Association. Stroke. 2024;55(12):344–424. https://www.ahajournals.org/doi/suppl/10.1161/STR.0000000000000475.
- Vindhyal MR, Ndunda PM, Munguti CM, Vindhyal SR, Okut H. Impact on cardiovascular outcomes among e-cigarette users: a review from national health interview surveys. J Am Coll Cardiol. 2019;73(9_Suppl 2)https://www.jacc.org/doi/10.1016/S0735-1097%2819%2933773-8
